When I switched FFover to the laptop I restricted my Addons to Xmarks (bookmarking) and Tidy HTML (validator).
These would probably slow loading time a bit, Xmarks accesses a server to automatically synchronise bookmarks but as far as I know this only happens when closing FF.
Strangely, straight after initiating this thread FF fired up reasonably quickly which indicates the problem is probably not FF itself but something else.
Re Chad's comment - I haven't had FF actually crash but I too have noticed that other browsers have caught up with FF in the speed stakes - I wonder if FF is succumbing to the "designed by a committee" syndrome or is it just getting bloated?
@ Shunned: thanks for the link, I've reduced my Java cache from 1000MB to 300MB, I'll see if that helps.