Having no gaps in the grid lines on the first or widest full pg rendering, then on a lower narrower pg break point settings having a gap or gaps in the grid lines. Is this an indication of a problem in the settings?

Please post a link to the page so that we can see it. It will make it much easier to know the issue.

Here is a link to the pg. It is the home pg of the site, it is published and is linked into all of the old VSD pgs of the site.
www.workhorsepainting.com
It is rendering properly without issues. I had many more grid line gaps in the lower part of the pg under the menu, probably 5 or so grid lines with gaps going across all 12 spans. I tweaked them out with many design setting changes to better align the design layout boxes and elements. Here is an a couple of attachments of grid lines with no gaps and grid lines with gaps. They are current screen shots from the current build upload. I am asking if the grid line gaps are something to be concerned about or if they can be ignored. Are grid line gaps an indication of a layout problem?

No, not at all

The grid lines are just indicators helping to organize and place the content elements. They are painted on the background of the rows, on the places where no row exists, if the row is smaller or if there's a margin between them, there will be not lines painted. The latter is what seems to be happening here.

Again, they are just helpers, not seeing them in certain spots is just fine

Thank you for answering my question. The grid line gaps was a nagging question that was persisting in my remake endeavors and it is good to have it squelched.