If you built the site originally with VSDv5.xx, maybe v6.xx, this is a problem that is most easily remedied by starting over. I hate to say it, but I've done just that on a couple of sites and it does clear up "some" of the issues. DO NOT cut and paste the old text to try and reconfigure it in VSDv7. You will develop brain damage.
Try to use the more common (standard) type faces (arial) and use common typeface sizes. Changing typefaces and picas of existing text is not good. If possible retype. You will still have to manually justify lines of text and paragraphs to make the end result properly legible on the end users side. Once you get used to making the adjustments you'll begin incorporating them during your initial build process and things will go much smoother. If it's manuscript text (a manifesto type document) then try using different sized text and different widths of galleys before you retype. This is an incident where It'd be nice to have full justification available like a word processor. If you want to reproduce your same text cut & paste it into a simple utility Word Processor like Notepad ( it renders in unformatted basic text). Re-Paste it into your VSDv7 website and then format the typefaces and picas
It's frustrating I know. I have a couple of pages on a site I'm working on now that look perfect once rendered online, however at first glance of the raw image in VSD you'd think there is no way this will ever reproduce correctly. I'm talking about integrated graphics in a page background that have to be offset about 2 inches to make them appear correctly live.
The real trick is adjusting them so they render in ALL the more common ( and not so common) flavors of browsers.
If you've never viewed your websites statistics then you're in for a surprise as to who's actually using your websites. User demographics have changed substantially in the last few years.
Redmond, OR - the High Desert