@ Steve. Thanks.
"The more I use the program the easier it gets Nigel. You will find it that way too. It takes me no time at all to bang out a grid."
I am with you there. But I noticed that once you've chosen a grid you are stuck to that. You cann't change it on the fly. Something I would love to do.
@G'kar. There are some arguments in favor for starting the design process with mobile first. It is leaner in the code and content distributed to the mobile devices. Although in de desktop-down approach you can set the visibility to none for elements it will still load on all devices. That is often to heavy for a phone, for instance.
The difficulty is that one has to deal with different page-designs and content hierarchy in between the breakpoints. am still struggling with that.
The perfection isn't reached in one pass.