<script src="https://ajax.googleapis.com/ajax/libs/jquery/1.7.1/jquery.min.js"></script>
<script type="text/javascript">
var jQ = $.noConflict(true);
jQ(document).ready(function(){
//The inputs you want read only
jQ('input[name="total1"]').attr('readonly', true);
jQ('input[name="total2"]').attr('readonly', true);
jQ('input[name="grand1"]').attr('readonly', true);

//inputs that will need to be calculated
jQ('input[name="qty1"]').addClass('cal');
jQ('input[name="qty2"]').addClass('cal');
jQ('input[name="price1"]').addClass('cal');
jQ('input[name="price2"]').addClass('cal');


jQ('.cal').bind('keyup keypress blur click',function(){

// Set variables for each input by name
var qty1 = jQ('input[name="qty1"]').val();
var qty2 = jQ('input[name="qty2"]').val();
var price1 = jQ('input[name="price1"]').val();
var price2 = jQ('input[name="price2"]').val();
//subtotal 1
var subtotal1 = (qty1 * price1);
if(subtotal1 > 0){
jQ('input[name="total1"]').val(subtotal1.toFixed(2));
}

// Subtotal 2
var subtotal2 = (qty2 * price2);
if(subtotal2 > 0){
jQ('input[name="total2"]').val(subtotal2.toFixed(2));
}
// Summing all the subtotals
var grandtotal = +subtotal1+ +subtotal2;

// This will be your grand total
if (grandtotal !== '' && !isNaN(grandtotal) && grandtotal > 0) {
jQ('input[name="grand1"]').val(grandtotal.toFixed(2));
}

});

});</script>